MSDS Name:   Ethyl methanesulfonate
Synonym:   Ethyl ester methanesulfonic acid; ethylmethane sulfonate; EMS.
Company:   AboutChem.com

**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****

+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
| 62-50-0 |Ethyl methanesulfonate | ca.100 | 200-536-7 |
+----------------+--------------------------------------+----------+-----------+
Hazard Symbols: XN
Risk Phrases: 22 40

**** SECTION 3 - HAZARDS IDENTIFICATION ****

EMERGENCY OVERVIEW
Harmful if swallowed. Limited evidence of a carcinogenic
effect.Mutagen.

Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
Harmful if swallowed. May cause irritation of the digestive tract.
Inhalation:
May cause respiratory tract irritation.
Chronic:
May cause cancer according to animal studies. Adverse reproductive
effects have been reported in animals. Laboratory experiments have
resulted in mutagenic effects.

**** SECTION 4 - FIRST AID MEASURES ****

Eyes:
Immediately flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15
minutes while removing contaminated clothing and shoes. Wash clothing
before reuse.
Ingestion:
Do not induce vomiting. If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Get medical aid immediately.
Inhalation:
Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
Antidote:
None reported.

**** SECTION 5 - FIRE FIGHTING MEASURES ****

General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. During a fire, irritating and highly toxic gases
may be generated by thermal decomposition or combustion. Will burn
if involved in a fire. Containers may explode in the heat of a fire.
Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or
alcohol-resistant foam.

**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****

General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Avoid runoff into storm sewers and
ditches which lead to waterways. Clean up spills immediately,
observing precautions in the Protective Equipment section. Provide
ventilation.

**** SECTION 7 - HANDLING and STORAGE ****

Handling:
Wash thoroughly after handling. Use with adequate ventilation. Avoid
contact with eyes, skin, and clothing. Keep container tightly closed.
Avoid ingestion and inhalation.
Storage:
Store in a cool, dry, well-ventilated area away from incompatible
substances. Keep containers tightly closed.

**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****

Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate
ventilation to keep airborne concentrations low.
Exposure Limits
CAS# 62-50-0:


Personal Protective Equipment

Eyes:
Wear safety glasses and chemical goggles if splashing
is possible.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.

**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****

Physical State: Liquid
Color: colorless
Odor: Not available.
pH: Not available.
Vapor Pressure: 0.328 mm Hg @ 25C
Viscosity: Not available.
Boiling Point: 86 deg C
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: 212 deg F ( 100.00 deg C)
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density: 1.167
Molecular Formula: CH3SO3C2H5
Molecular Weight: 124.1142

**** SECTION 10 - STABILITY AND REACTIVITY ****

Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents, strong bases.
Hazardous Decomposition Products:
Carbon monoxide, oxides of sulfur, carbon dioxide.
Hazardous Polymerization: Has not been reported

**** SECTION 11 - TOXICOLOGICAL INFORMATION ****

RTECS#:
CAS# 62-50-0: PB2100000
LD50/LC50:
CAS# 62-50-0: Oral, mouse: LD50 = 470 mg/kg.
Not available.
Carcinogenicity:
Ethyl methanesulfonate -
California: carcinogen, initial date 1/1/88
NTP: Suspect carcinogen
IARC: Group 2B carcinogen
Other:
See actual entry in RTECS for complete information.

**** SECTION 12 - ECOLOGICAL INFORMATION ****

Ecotoxicity:
Based on a Log KOW=0.09, BCF of <1 was estimated for ethyl
methanesulfonate.

**** SECTION 13 - DISPOSAL CONSIDERATIONS ****

Dispose of in a manner consistent with federal, state, and local regulations.

**** SECTION 14 - TRANSPORT INFORMATION ****

IATA
Shipping Name: Not Regulated
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not Regulated
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not Regulated
Hazard Class:
UN Number:
Packing group:
USA RQ: CAS# 62-50-0: 1 lb final RQ; 0.454 kg final RQ

**** SECTION 15 - REGULATORY INFORMATION ****

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XN
Risk Phrases:
R 22 Harmful if swallowed.
R 40 Limited evidence of a carcinogenic effect.
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
S 45 In case of accident or if you feel unwell, seek
medical advice immediately (show the label where
possible).
WGK (Water Danger/Protection)
CAS# 62-50-0: No information available.
Canada
CAS# 62-50-0 is listed on Canada's DSL List.
CAS# 62-50-0 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 62-50-0 is listed on the TSCA inventory.

**** SECTION 16 - ADDITIONAL INFORMATION ****

MSDS Creation Date: 1/28/1999 Revision #5 Date: 12/01/2004

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