MSDS Name:   HOBt/NMP (1.0M, 1-Hydroxybenzotriazole / 1-Methyl-2-pyrrolidone
Synonym:   None Known.
Company:   AboutChem.com

**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****

+----------------+--------------------------------------+----------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|----------------|--------------------------------------|----------|-----------|
|----------------|--------------------------------------|----------|-----------|
| 872-50-4 |1-Methyl-2-pyrrolidone | 86% | 212-828-1 |
|----------------|--------------------------------------|----------|-----------|
| 2592-95-2 |1-Hydroxybenzotriazole | 14% | 219-989-7 |
+----------------+--------------------------------------+----------+-----------+
Text for R-phrases: see Section 16
Hazard Symbols: XI
Risk Phrases: 10 36/38 5

**** SECTION 3 - HAZARDS IDENTIFICATION ****

EMERGENCY OVERVIEW
Flammable. Irritating to eyes and skin. Heating may cause an
explosion.Hygroscopic (absorbs moisture from the air).Light
sensitive.

Potential Health Effects
Eye:
Causes eye irritation. May cause temporary corneal clouding.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Not expected to cause an allergic skin reaction.
Ingestion:
May cause irritation of the digestive tract. May cause
gastrointestinal irritation with nausea, vomiting and diarrhea. May
be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled. May
cause headache.
Chronic:
Prolonged or repeated skin contact may cause dermatitis. Adverse
reproductive effects have been reported in animals.

**** SECTION 4 - FIRST AID MEASURES ****

Eyes:
In case of contact, immediately flush eyes with plenty of water for
at least 15 minutes. Get medical aid.
Skin:
In case of contact, flush skin with plenty of water. Remove
contaminated clothing and shoes. Get medical aid if irritation
develops and persists. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by
medical personnel. Never give anything by mouth to an unconscious
person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

**** SECTION 5 - FIRE FIGHTING MEASURES ****

General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Vapors can travel to a source of ignition and flash
back. During a fire, irritating and highly toxic gases may be
generated by thermal decomposition or combustion. Will burn if
involved in a fire. Flammable liquid and vapor.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or appropriate foam.

**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****

General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth),
then place in suitable container. Avoid runoff into storm sewers and
ditches which lead to waterways. Remove all sources of ignition. Use
a spark-proof tool. Provide ventilation.

**** SECTION 7 - HANDLING and STORAGE ****

Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use with adequate ventilation. Ground and bond
containers when transferring material. Use spark-proof tools and
explosion proof equipment. Avoid contact with eyes, skin, and
clothing. Empty containers retain product residue, (liquid and/or
vapor), and can be dangerous. Do not pressurize, cut, weld, braze,
solder, drill, grind, or expose empty containers to heat, sparks or
open flames. Keep away from heat, sparks and flame. Keep away from
heat and flame. Avoid breathing vapor or mist.
Storage:
Keep away from sources of ignition. Keep container closed when not
in use. Refrigerator/flammables.

**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****

Engineering Controls:
Facilities storing or utilizing this material should be equipped
with an eyewash facility and a safety shower. Use adequate general or
local explosion-proof ventilation to keep airborne levels to
acceptable levels.
Exposure Limits
CAS# 872-50-4:
United Kingdom, WEL - TWA: 25 ppm TWA; 103 mg/m3 TWA
United Kingdom, WEL - STEL: 75 ppm STEL; 309 mg/m3 STEL

Germany: 19 ppm TWA (steam); 80 mg/m3 TWA (steam)
Germany: Skin absorber
Japan: 1 ppm OEL; 4 mg/m3 OEL
Netherlands: 20 ppm MAC; 80 mg/m3 MAC (fume)
Russia: 100 mg/m3 TWA
Spain: 25 ppm VLA-ED; 103 mg/m3 VLA-ED
Spain: 75 ppm VLA-EC; 309 mg/m3 VLA-EC
CAS# 2592-95-2:


Personal Protective Equipment

Eyes:
Wear chemical splash goggles.
Skin:
Wear appropriate gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29
CFR 1910.134 or European Standard EN 149. Use a
NIOSH/MSHA or European Standard EN 149 approved
respirator if exposure limits are exceeded or if
irritation or other symptoms are experienced.

**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****

Physical State: Liquid
Color: colorless
Odor: amine-like
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: Soluble.
Specific Gravity/Density:
Molecular Formula: Solution
Molecular Weight: 0

**** SECTION 10 - STABILITY AND REACTIVITY ****

Chemical Stability:
Stable at room temperature in closed containers under normal storage
and handling conditions. Heating may cause an explosion. Light
sensitive. Hygroscopic: absorbs moisture or water from the air.
Conditions to Avoid:
Light, ignition sources, excess heat, exposure to moist air or water.
Incompatibilities with Other Materials:
Strong oxidizing agents, acids.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Will not occur.

**** SECTION 11 - TOXICOLOGICAL INFORMATION ****

RTECS#:
CAS# 872-50-4: UY5790000
CAS# 2592-95-2: DM1288000
LD50/LC50:
CAS# 872-50-4: Draize test, rabbit, eye: 100 mg Moderate; Oral,
mouse: LD50 = 5130 mg/kg; Oral, rat: LD50 = 3914 mg/kg; Skin,
rabbit: LD50 = 8 gm/kg.
CAS# 2592-95-2: Draize test, rabbit, eye: 100 mg Mild.
Sensitization test (guinea pig): negative.
negative.(Merck)
Carcinogenicity:
1-Methyl-2-pyrrolidone -
Not listed by ACGIH, IARC, or NTP.
1-Hydroxybenzotriazole -
Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

**** SECTION 12 - ECOLOGICAL INFORMATION ****

Ecotoxicity:
Daphnia: Daphnia: 4897 mg/l; 48 h; EC50Fish: Gold orfe: 4000 mg/l; 96
h; LC50Bacteria: >9000 mg/l; 48 h; EC50Algae: >500 mg/l; 72 h; IC50

**** SECTION 13 - DISPOSAL CONSIDERATIONS ****

Dispose of in a manner consistent with federal, state, and local regulations.

**** SECTION 14 - TRANSPORT INFORMATION ****

IATA
Shipping Name: FLAMMABLE LIQUID, N.O.S.
Hazard Class: 3
UN Number: 1993
Packing Group: III
IMO
Shipping Name: FLAMMABLE LIQUID, N.O.S.
Hazard Class: 3
UN Number: 1993
Packing Group: III
RID/ADR
Shipping Name: FLAMMABLE LIQUID, N.O.S.
Hazard Class: 3
UN Number: 1993
Packing group: III

**** SECTION 15 - REGULATORY INFORMATION ****

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 10 Flammable.
R 36/38 Irritating to eyes and skin.
R 5 Heating may cause an explosion.
Safety Phrases:
S 7/9 Keep container tightly closed and in a
well-ventilated place.
S 41 In case of fire and/or explosion do not breathe
fumes.
WGK (Water Danger/Protection)
CAS# 872-50-4: 1
CAS# 2592-95-2: No information available.
Canada
CAS# 872-50-4 is listed on Canada's DSL List.
CAS# 2592-95-2 is listed on Canada's DSL List.
CAS# 872-50-4 is not listed on Canada's Ingredient Disclosure List.
CAS# 2592-95-2 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 872-50-4 is listed on the TSCA inventory.
CAS# 2592-95-2 is listed on the TSCA inventory.

**** SECTION 16 - ADDITIONAL INFORMATION ****

Text for R-phrases from Section 2
MSDS Creation Date: 3/01/2004 Revision #2 Date: 3/01/2004

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